IDRA 21

Product Name: IDRA 21
CAS No.: 22503-72-6
Chemical Name: IDRA 21
Synonyms: AMPAKINE;IDRA 21;IDRA 21,98%;S-18986 IDRA-21 AMPAKINE;7-CHLORO-3-METHYL-3,4-DIHYDRO-2H-1,2,4-BENZOTHIADIAZINE;7-chloro-3-methyl-3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-...;7-CHLORO-3-METHYL-3,4-DIHYDRO-2H-1,2,4-BENZOTHIADIAZINE S,S-DIOXIDE;7-CHLORO-3-METHYL-3,4-DIHYDRO-2H-1,2,4-BENZOTHIADIAZINE 1,1-DIOXIDE;7-Chloro-3,4-dihydro-3-methyl-2H-1,2,4-benzothiadiazine 1,1-dioxide;2H-1,2,4-Benzothiadiazine,7-chloro-3,4-dihydro-3-Methyl-, 1,1-dioxide
CBNumber: CB3468324
Molecular Formula: C8H9ClN2O2S
Formula Weight: 232.69
MOL File: 22503-72-6.mol

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IDRA 21 Property

Melting point:: 209 °C(Solv: acetic acid (64-19-7))
Boiling point:: 405.1±55.0 °C(Predicted)
Density: 1.394±0.06 g/cm3(Predicted)
storage temp.: Keep in dark place,Inert atmosphere,Room temperature
solubility: DMSO (Slightly), Methanol (Slightly, Sonicated)
form: Solid
pka: 9.78±0.40(Predicted)
color: Off-White to Pale Yellow
InChIKey: VZRNTCHTJRLTMU-UHFFFAOYSA-N

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Safety

Safety Statements: 24/25
WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: I5773
Product name: IDRA 21
Purity: ≥98%
Packaging: 5mg
Price: $210
Updated: 2024/03/01

Tocris

Product number: 1219
Product name: IDRA 21
Purity: ≥98%(HPLC)
Packaging: 10
Price: $183
Updated: 2021/12/16

Tocris

Product number: 1219
Product name: IDRA 21
Purity: ≥98%(HPLC)
Packaging: 50
Price: $770
Updated: 2021/12/16

Usbiological

Product number: 255490
Product name: IDRA 21
Packaging: 10mg
Price: $423
Updated: 2021/12/16

TRC

Product number: I232500
Product name: IDRA 21
Packaging: 250mg
Price: $1540
Updated: 2021/12/16

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IDRA 21 Chemical Properties,Usage,Production

Chemical Properties

white to off-white crystalline powder

Uses

IDRA-21 is a benzothiadiazine derivative and a positive allosteric modulator of glutamate AMPA receptors (1,2,3,4). It is able to increase excitatory synaptic strength by inhibiting AMPA receptor desensitization. IDRA 21 may exhibit therapeutic effects to ameliorate memory deficits in patients with cognitive impairments such as Alzheimer''s disease.

Uses

IDRA-21 inhibits AMPA receptor desensitization and enhances cognition by a related mechanism. IDRA-21 is more able to cross the blood-brain barrier than Cyclothiazide (C988960).

Definition

ChEBI: 7-chloro-3-methyl-3,4-dihydro-2H-1$l^{6},2,4-benzothiadiazine 1,1-dioxide is a benzothiadiazine.

Biological Activity

Inhibits AMPA receptor desensitization and enhances cognition by a related mechanism. More able to cross the blood-brain barrier than cyclothiazide (6-Chloro-3,4-dihydro-3-(5-norbornen-2-yl)-2H-1,2,4-benzothiazidiazine-7-sulfonamide-1,1-dioxide ).

storage

Room temperature

IDRA 21 Preparation Products And Raw materials

Raw materials

Preparation Products

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IDRA 21 Suppliers

Canada 1 China 121 Germany 1 India 3 Japan 1 Switzerland 3 United Kingdom 3 United States 11 Global 144

EMMX Biotechnology LLC

Tel: 888-539-0666
Fax: 888-539-0666
Email: info@emmx.com
Country: United States
ProdList: 8449
Advantage: 60

InvivoChem

Tel: +1-708-310-1919 +1-13798911105
Fax: 708-557-7486
Email: sales@invivochem.cn
Country: United States
ProdList: 6393
Advantage: 58

Aladdin Scientific

Tel: +1-833-552-7181
Email: sales@aladdinsci.com
Country: United States
ProdList: 57511
Advantage: 58

TargetMol Chemicals Inc.

Tel: +1-781-999-5354
Email: support@targetmol.com
Country: United States
ProdList: 19973
Advantage: 58

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View Lastest Price from IDRA 21 manufacturers

Wuhan Haorong Biotechnology Co.,Ltd

Product: IDRA 21 22503-72-6
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 500
Release date: 2023-08-02

Hebei Dangtong Import and export Co LTD

Product: IDRA 21 22503-72-6
Price: US $12.00-10.00/Grams
Min. Order: 50Grams
Purity: 99.99%
Supply Ability: 100Tons
Release date: 2023-03-17

Hebei Mojin Biotechnology Co.,Ltd

Product: IDRA 21 22503-72-6
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 50000KG/month
Release date: 2024-05-16

22503-72-6, IDRA 21Related Search:

Methyltrichlorosilane Benzyl chloride Triphosgene IDRA 21 2-Amino-5-chlorobenzenesulfonamide

IDRA 21

IDRA 21,7-Chloro-3-methyl-3,4-dihydro-2H-1,2,4-benzothiadiazineS,S-dioxide

7-CHLORO-3-METHYL-3,4-DIHYDRO-2H-1,2,4-BENZOTHIADIAZINE

7-CHLORO-3-METHYL-3,4-DIHYDRO-2H-1,2,4-BENZOTHIADIAZINE 1,1-DIOXIDE

7-CHLORO-3-METHYL-3,4-DIHYDRO-2H-1,2,4-BENZOTHIADIAZINE S,S-DIOXIDE

IDRA 21,98%

7-chloro-3-methyl-3,4-dihydro-2H-benzo[e][1,2,4]thiadiazine 1,1-dioxide

7-Chloro-3,4-dihydro-3-methyl-2H-1,2,4-benzothiadiazine 1,1-dioxide

2H-1,2,4-Benzothiadiazine,7-chloro-3,4-dihydro-3-Methyl-, 1,1-dioxide

AMPAKINE

7-chloro-3-methyl-3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-...

IDRA 21 Benzothiadiazine,7-chloro- 3,4-dihydro-3-methyl-,1,1- dioxide

S-18986 IDRA-21 AMPAKINE

22503-72-6

Ligand-Gated Ion Channels

Ion Channels

Ionotropic Glutamate Receptor Modulators

Cell Signaling and Neuroscience

Cell Biology

BioChemical

API